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A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial

Identificadores del recurso

Isetta Valentina, Negrin Miguel A., Monasterio Carmen, Masa Juan F., Feu Nuria, Alvarez Ainhoa, et al. A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial. Thorax. 2015 Nov;70(11):1054-1061. Epub 2015 Aug 26.

0040-6376

http://hdl.handle.net/20.500.13003/10635

10.1136/thoraxjnl-2015-207032

1468-3296

26310452

L606451071

2-s2.0-84945185119

000364711000007

Procedencia

(Docusalut. Repositorio institucional del sistema sanitario público de las Islas Baleares)

Ficha

Título:: A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial
Tema:: Continuous Positive Airway Pressure; Sleep Apnea, Obstructive; Follow-Up Studies; Humans; Bayes Theorem; Cost-Benefit Analysis; Middle Aged; Male; Quality of Life; Prospective Studies; Patient Compliance; Female; Sleep; Telemedicine; Disease Management; Sueño; Manejo de la Enfermedad; Telemedicina; Femenino; Presión de las Vías Aéreas Positiva Contínua; Análisis Costo-Beneficio; Masculino; Estudios de Seguimiento; Apnea Obstructiva del Sueño; Cooperación del Paciente; Humanos; Persona de Mediana Edad; Calidad de Vida; Estudios Prospectivos; Teorema de Bayes
Descrición:: Background Compliance with continuous positive airway pressure (CPAP) therapy is essential in patients with obstructive sleep apnoea (OSA), but adequate control is not always possible. This is clinically important because CPAP can reverse the morbidity and mortality associated with OSA. Telemedicine, with support provided via a web platform and video conferences, could represent a cost-effective alternative to standard care management. Aim To assess the telemedicine impact on treatment compliance, cost-effectiveness and improvement in quality of life (QoL) when compared with traditional face-to-face follow-up. Methods A randomised controlled trial was performed to compare a telemedicine-based CPAP follow-up strategy with standard face-to-face management. Consecutive OSA patients requiring CPAP treatment, with sufficient internet skills and who agreed to participate, were enrolled. They were followed-up at 1, 3 and 6 months and answered surveys about sleep, CPAP side effects and lifestyle. We compared CPAP compliance, cost-effectiveness and QoL between the beginning and the end of the study. A Bayesian cost-effectiveness analysis with non-informative priors was performed. Results We randomised 139 patients. At 6 months, we found similar levels of CPAP compliance, and improved daytime sleepiness, QoL, side effects and degree of satisfaction in both groups. Despite requiring more visits, the telemedicine group was more cost-effective: costs were lower and differences in effectiveness were not relevant. Conclusions A telemedicine-based strategy for the follow-up of CPAP treatment in patients with OSA was as effective as standard hospital-based care in terms of CPAP compliance and symptom improvement, with comparable side effects and satisfaction rates. The telemedicine-based strategy had lower total costs due to savings on transport and less lost productivity (indirect costs).; This project was supported by SEPAR/FIS PI14/00416 and ECO2013-47092 (MINECO, Spain).
Idioma:: English
Relación:: https://dx.doi.org/10.1136/thoraxjnl-2015-207032
Autor/Productor:: Isetta, Valentina; Negrin, Miguel A.; Monasterio, Carmen; Masa, Juan F.; Feu, Nuria; Alvarez, Ainhoa; Campos-Rodriguez, Francisco; Ruiz, Concepcion; Abad, Jorge; Vazquez-Polo, Francisco J.; Farre, Ramon; Galdeano, Marina; Lloberes, Patricia; Embid, Cristina; de la Pena, Monica; Puertas, Javier; Dalmases, Mireia; Salord, Neus; Corral, Jaime; Jurado, Bernabe; Leon, Carmen; Egea, Carlos; Munoz, Aida; Parra, Olga; Cambrodi, Roser; Martel-Escobar, Maria; Arque, Meritxell; Montserrat, Josep M.; Spanish Sleep Network
Editor:: BMJ Publishing Group
Data:: 2021-08-24T15:55:40Z; 2015-11
Tipo de recurso:: research article

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1. <dc:title>A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial</dc:title>
2. <dc:creator>Isetta, Valentina</dc:creator>
3. <dc:creator>Negrin, Miguel A.</dc:creator>
4. <dc:creator>Monasterio, Carmen</dc:creator>
5. <dc:creator>Masa, Juan F.</dc:creator>
6. <dc:creator>Feu, Nuria</dc:creator>
7. <dc:creator>Alvarez, Ainhoa</dc:creator>
8. <dc:creator>Campos-Rodriguez, Francisco</dc:creator>
9. <dc:creator>Ruiz, Concepcion</dc:creator>
10. <dc:creator>Abad, Jorge</dc:creator>
11. <dc:creator>Vazquez-Polo, Francisco J.</dc:creator>
12. <dc:creator>Farre, Ramon</dc:creator>
13. <dc:creator>Galdeano, Marina</dc:creator>
14. <dc:creator>Lloberes, Patricia</dc:creator>
15. <dc:creator>Embid, Cristina</dc:creator>
16. <dc:creator>de la Pena, Monica</dc:creator>
17. <dc:creator>Puertas, Javier</dc:creator>
18. <dc:creator>Dalmases, Mireia</dc:creator>
19. <dc:creator>Salord, Neus</dc:creator>
20. <dc:creator>Corral, Jaime</dc:creator>
21. <dc:creator>Jurado, Bernabe</dc:creator>
22. <dc:creator>Leon, Carmen</dc:creator>
23. <dc:creator>Egea, Carlos</dc:creator>
24. <dc:creator>Munoz, Aida</dc:creator>
25. <dc:creator>Parra, Olga</dc:creator>
26. <dc:creator>Cambrodi, Roser</dc:creator>
27. <dc:creator>Martel-Escobar, Maria</dc:creator>
28. <dc:creator>Arque, Meritxell</dc:creator>
29. <dc:creator>Montserrat, Josep M.</dc:creator>
30. <dc:creator>Spanish Sleep Network</dc:creator>
31. <dc:subject>Continuous Positive Airway Pressure</dc:subject>
32. <dc:subject>Sleep Apnea, Obstructive</dc:subject>
33. <dc:subject>Follow-Up Studies</dc:subject>
34. <dc:subject>Humans</dc:subject>
35. <dc:subject>Bayes Theorem</dc:subject>
36. <dc:subject>Cost-Benefit Analysis</dc:subject>
37. <dc:subject>Middle Aged</dc:subject>
38. <dc:subject>Male</dc:subject>
39. <dc:subject>Quality of Life</dc:subject>
40. <dc:subject>Prospective Studies</dc:subject>
41. <dc:subject>Patient Compliance</dc:subject>
42. <dc:subject>Female</dc:subject>
43. <dc:subject>Sleep</dc:subject>
44. <dc:subject>Telemedicine</dc:subject>
45. <dc:subject>Disease Management</dc:subject>
46. <dc:subject>Sueño</dc:subject>
47. <dc:subject>Manejo de la Enfermedad</dc:subject>
48. <dc:subject>Telemedicina</dc:subject>
49. <dc:subject>Femenino</dc:subject>
50. <dc:subject>Presión de las Vías Aéreas Positiva Contínua</dc:subject>
51. <dc:subject>Análisis Costo-Beneficio</dc:subject>
52. <dc:subject>Masculino</dc:subject>
53. <dc:subject>Estudios de Seguimiento</dc:subject>
54. <dc:subject>Apnea Obstructiva del Sueño</dc:subject>
55. <dc:subject>Cooperación del Paciente</dc:subject>
56. <dc:subject>Humanos</dc:subject>
57. <dc:subject>Persona de Mediana Edad</dc:subject>
58. <dc:subject>Calidad de Vida</dc:subject>
59. <dc:subject>Estudios Prospectivos</dc:subject>
60. <dc:subject>Teorema de Bayes</dc:subject>
61. <dc:description>Background Compliance with continuous positive airway pressure (CPAP) therapy is essential in patients with obstructive sleep apnoea (OSA), but adequate control is not always possible. This is clinically important because CPAP can reverse the morbidity and mortality associated with OSA. Telemedicine, with support provided via a web platform and video conferences, could represent a cost-effective alternative to standard care management. Aim To assess the telemedicine impact on treatment compliance, cost-effectiveness and improvement in quality of life (QoL) when compared with traditional face-to-face follow-up. Methods A randomised controlled trial was performed to compare a telemedicine-based CPAP follow-up strategy with standard face-to-face management. Consecutive OSA patients requiring CPAP treatment, with sufficient internet skills and who agreed to participate, were enrolled. They were followed-up at 1, 3 and 6 months and answered surveys about sleep, CPAP side effects and lifestyle. We compared CPAP compliance, cost-effectiveness and QoL between the beginning and the end of the study. A Bayesian cost-effectiveness analysis with non-informative priors was performed. Results We randomised 139 patients. At 6 months, we found similar levels of CPAP compliance, and improved daytime sleepiness, QoL, side effects and degree of satisfaction in both groups. Despite requiring more visits, the telemedicine group was more cost-effective: costs were lower and differences in effectiveness were not relevant. Conclusions A telemedicine-based strategy for the follow-up of CPAP treatment in patients with OSA was as effective as standard hospital-based care in terms of CPAP compliance and symptom improvement, with comparable side effects and satisfaction rates. The telemedicine-based strategy had lower total costs due to savings on transport and less lost productivity (indirect costs).</dc:description>
62. <dc:description>This project was supported by SEPAR/FIS PI14/00416 and ECO2013-47092 (MINECO, Spain).</dc:description>
63. <dc:date>2021-08-24T15:55:40Z</dc:date>
64. <dc:date>2021-08-24T15:55:40Z</dc:date>
65. <dc:date>2015-11</dc:date>
66. <dc:type>research article</dc:type>
67. <dc:identifier>Isetta Valentina, Negrin Miguel A., Monasterio Carmen, Masa Juan F., Feu Nuria, Alvarez Ainhoa, et al. A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial. Thorax. 2015 Nov;70(11):1054-1061. Epub 2015 Aug 26.</dc:identifier>
68. <dc:identifier>0040-6376</dc:identifier>
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42. <dim:field element="description" lang="en" mdschema="dc" qualifier="abstract">Background Compliance with continuous positive airway pressure (CPAP) therapy is essential in patients with obstructive sleep apnoea (OSA), but adequate control is not always possible. This is clinically important because CPAP can reverse the morbidity and mortality associated with OSA. Telemedicine, with support provided via a web platform and video conferences, could represent a cost-effective alternative to standard care management. Aim To assess the telemedicine impact on treatment compliance, cost-effectiveness and improvement in quality of life (QoL) when compared with traditional face-to-face follow-up. Methods A randomised controlled trial was performed to compare a telemedicine-based CPAP follow-up strategy with standard face-to-face management. Consecutive OSA patients requiring CPAP treatment, with sufficient internet skills and who agreed to participate, were enrolled. They were followed-up at 1, 3 and 6 months and answered surveys about sleep, CPAP side effects and lifestyle. We compared CPAP compliance, cost-effectiveness and QoL between the beginning and the end of the study. A Bayesian cost-effectiveness analysis with non-informative priors was performed. Results We randomised 139 patients. At 6 months, we found similar levels of CPAP compliance, and improved daytime sleepiness, QoL, side effects and degree of satisfaction in both groups. Despite requiring more visits, the telemedicine group was more cost-effective: costs were lower and differences in effectiveness were not relevant. Conclusions A telemedicine-based strategy for the follow-up of CPAP treatment in patients with OSA was as effective as standard hospital-based care in terms of CPAP compliance and symptom improvement, with comparable side effects and satisfaction rates. The telemedicine-based strategy had lower total costs due to savings on transport and less lost productivity (indirect costs).</dim:field>
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1. <title>A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial</title>
2. <creator>Isetta, Valentina</creator>
3. <creator>Negrin, Miguel A.</creator>
4. <creator>Monasterio, Carmen</creator>
5. <creator>Masa, Juan F.</creator>
6. <creator>Feu, Nuria</creator>
7. <creator>Alvarez, Ainhoa</creator>
8. <creator>Campos-Rodriguez, Francisco</creator>
9. <creator>Ruiz, Concepcion</creator>
10. <creator>Abad, Jorge</creator>
11. <creator>Vazquez-Polo, Francisco J.</creator>
12. <creator>Farre, Ramon</creator>
13. <creator>Galdeano, Marina</creator>
14. <creator>Lloberes, Patricia</creator>
15. <creator>Embid, Cristina</creator>
16. <creator>de la Pena, Monica</creator>
17. <creator>Puertas, Javier</creator>
18. <creator>Dalmases, Mireia</creator>
19. <creator>Salord, Neus</creator>
20. <creator>Corral, Jaime</creator>
21. <creator>Jurado, Bernabe</creator>
22. <creator>Leon, Carmen</creator>
23. <creator>Egea, Carlos</creator>
24. <creator>Munoz, Aida</creator>
25. <creator>Parra, Olga</creator>
26. <creator>Cambrodi, Roser</creator>
27. <creator>Martel-Escobar, Maria</creator>
28. <creator>Arque, Meritxell</creator>
29. <creator>Montserrat, Josep M.</creator>
30. <creator>Spanish Sleep Network</creator>
31. <description>Background Compliance with continuous positive airway pressure (CPAP) therapy is essential in patients with obstructive sleep apnoea (OSA), but adequate control is not always possible. This is clinically important because CPAP can reverse the morbidity and mortality associated with OSA. Telemedicine, with support provided via a web platform and video conferences, could represent a cost-effective alternative to standard care management. Aim To assess the telemedicine impact on treatment compliance, cost-effectiveness and improvement in quality of life (QoL) when compared with traditional face-to-face follow-up. Methods A randomised controlled trial was performed to compare a telemedicine-based CPAP follow-up strategy with standard face-to-face management. Consecutive OSA patients requiring CPAP treatment, with sufficient internet skills and who agreed to participate, were enrolled. They were followed-up at 1, 3 and 6 months and answered surveys about sleep, CPAP side effects and lifestyle. We compared CPAP compliance, cost-effectiveness and QoL between the beginning and the end of the study. A Bayesian cost-effectiveness analysis with non-informative priors was performed. Results We randomised 139 patients. At 6 months, we found similar levels of CPAP compliance, and improved daytime sleepiness, QoL, side effects and degree of satisfaction in both groups. Despite requiring more visits, the telemedicine group was more cost-effective: costs were lower and differences in effectiveness were not relevant. Conclusions A telemedicine-based strategy for the follow-up of CPAP treatment in patients with OSA was as effective as standard hospital-based care in terms of CPAP compliance and symptom improvement, with comparable side effects and satisfaction rates. The telemedicine-based strategy had lower total costs due to savings on transport and less lost productivity (indirect costs).</description>
32. <date>2021-08-24</date>
33. <date>2021-08-24</date>
34. <date>2015-11</date>
35. <type>research article</type>
36. <identifier>Isetta Valentina, Negrin Miguel A., Monasterio Carmen, Masa Juan F., Feu Nuria, Alvarez Ainhoa, et al. A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial. Thorax. 2015 Nov;70(11):1054-1061. Epub 2015 Aug 26.</identifier>
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1. <dc:title>A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial</dc:title>
2. <dc:creator>Isetta, Valentina</dc:creator>
3. <dc:creator>Negrin, Miguel A.</dc:creator>
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28. <dc:creator>Arque, Meritxell</dc:creator>
29. <dc:creator>Montserrat, Josep M.</dc:creator>
30. <dc:creator>Spanish Sleep Network</dc:creator>
31. <dcterms:abstract>Background Compliance with continuous positive airway pressure (CPAP) therapy is essential in patients with obstructive sleep apnoea (OSA), but adequate control is not always possible. This is clinically important because CPAP can reverse the morbidity and mortality associated with OSA. Telemedicine, with support provided via a web platform and video conferences, could represent a cost-effective alternative to standard care management. Aim To assess the telemedicine impact on treatment compliance, cost-effectiveness and improvement in quality of life (QoL) when compared with traditional face-to-face follow-up. Methods A randomised controlled trial was performed to compare a telemedicine-based CPAP follow-up strategy with standard face-to-face management. Consecutive OSA patients requiring CPAP treatment, with sufficient internet skills and who agreed to participate, were enrolled. They were followed-up at 1, 3 and 6 months and answered surveys about sleep, CPAP side effects and lifestyle. We compared CPAP compliance, cost-effectiveness and QoL between the beginning and the end of the study. A Bayesian cost-effectiveness analysis with non-informative priors was performed. Results We randomised 139 patients. At 6 months, we found similar levels of CPAP compliance, and improved daytime sleepiness, QoL, side effects and degree of satisfaction in both groups. Despite requiring more visits, the telemedicine group was more cost-effective: costs were lower and differences in effectiveness were not relevant. Conclusions A telemedicine-based strategy for the follow-up of CPAP treatment in patients with OSA was as effective as standard hospital-based care in terms of CPAP compliance and symptom improvement, with comparable side effects and satisfaction rates. The telemedicine-based strategy had lower total costs due to savings on transport and less lost productivity (indirect costs).</dcterms:abstract>
32. <dcterms:dateAccepted>2021-08-24T15:55:40Z</dcterms:dateAccepted>
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34. <dcterms:created>2021-08-24T15:55:40Z</dcterms:created>
35. <dcterms:issued>2015-11</dcterms:issued>
36. <dc:type>research article</dc:type>
37. <dc:identifier>Isetta Valentina, Negrin Miguel A., Monasterio Carmen, Masa Juan F., Feu Nuria, Alvarez Ainhoa, et al. A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial. Thorax. 2015 Nov;70(11):1054-1061. Epub 2015 Aug 26.</dc:identifier>
38. <dc:identifier>0040-6376</dc:identifier>
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  13. <dc:creator>Galdeano, Marina</dc:creator>
  14. <dc:creator>Lloberes, Patricia</dc:creator>
  15. <dc:creator>Embid, Cristina</dc:creator>
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  31. <dc:description>Background Compliance with continuous positive airway pressure (CPAP) therapy is essential in patients with obstructive sleep apnoea (OSA), but adequate control is not always possible. This is clinically important because CPAP can reverse the morbidity and mortality associated with OSA. Telemedicine, with support provided via a web platform and video conferences, could represent a cost-effective alternative to standard care management. Aim To assess the telemedicine impact on treatment compliance, cost-effectiveness and improvement in quality of life (QoL) when compared with traditional face-to-face follow-up. Methods A randomised controlled trial was performed to compare a telemedicine-based CPAP follow-up strategy with standard face-to-face management. Consecutive OSA patients requiring CPAP treatment, with sufficient internet skills and who agreed to participate, were enrolled. They were followed-up at 1, 3 and 6 months and answered surveys about sleep, CPAP side effects and lifestyle. We compared CPAP compliance, cost-effectiveness and QoL between the beginning and the end of the study. A Bayesian cost-effectiveness analysis with non-informative priors was performed. Results We randomised 139 patients. At 6 months, we found similar levels of CPAP compliance, and improved daytime sleepiness, QoL, side effects and degree of satisfaction in both groups. Despite requiring more visits, the telemedicine group was more cost-effective: costs were lower and differences in effectiveness were not relevant. Conclusions A telemedicine-based strategy for the follow-up of CPAP treatment in patients with OSA was as effective as standard hospital-based care in terms of CPAP compliance and symptom improvement, with comparable side effects and satisfaction rates. The telemedicine-based strategy had lower total costs due to savings on transport and less lost productivity (indirect costs).</dc:description>
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